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Pharmaceutical Applications

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There are numerous applications in the pharmaceutical market that can be accomplished with XRF. There are many drugs that have a heavy element (>Z=10) associated with them so that the concentration is easily monitored.

Iron Testing

Bismuth in Anti-Diarrheal Medication
Bismuth is a heavy metal that is easily monitored by EDXRF instrument.

Calcium and Magnesium in Antacids
Calcium and/or magnesium are found in high concentrations in most antacid products and can be measured with EDXRF instruments.

Zirconium, and Aluminum in Deodorant
Most deodorants contain zirconium, and/or aluminum at high concentration. In many formulations silicon and chlorine are also measurable. Deodorants have long been analyzed by EDXRF.

Selenium in Shampoo
Selenium is a common additive in shampoos to prevent dandruff. EDXRF has long been used in this application.

Lead in Bone and Blood
There is a patented XRF method for measuring lead in bone by directly fluorescing an area near the knee. Toxic levels of lead in blood are also detectable by XRF.

Calcium in Dietary Supplements
Calcium is added to dietary supplements as a source of calcium to help with the prevention of osteoporosis.

Pharmaceutical Analysis
Chlorine in Toothpaste
Toothpaste is another product that has been successfully analyzed by EDXRF.

Zinc in Cold Treatments
Zinc is a common cold remedied that is available in many lozenges and in other forms. The zinc concentration is high and can be monitored by EDXRF.

Metals in Vitamin tablets and supplements
Metal concentrations in vitamin tables can be measured with EDXRF instruments.

Iodine in Sterilization Products
Iodine is toxic and has long been used in sterilizing solutions. Iodine can be measured with EDXRF instruments.

Silver Nitrate on Medical Products
Most plastic or rubber medical products contain silver nitrate as a biocide agent to prevent the spread of disease. A few examples are EKG strips, catheters, and contact lenses. The concentration is in the PPM range, but may be measured by EDXRF.

Hazardous Metal Analysis in Pharmaceuticals
All products have to be free of toxic metals such as lead, mercury, cadmium, and arsenic. EDXRF instruments have detection limits that are good enough to determine if products are non-toxic.

Silicone on Condoms
Silicone is a release agent applied to most condoms to keep the latex from sticking to itself. The coating is light, but measurable by EDXRF.

Nickel and Vanadium in Crude Oil
These elements can poison catalysts used in the refining process. Less than 5 PPM concentrations are preferred. EDXRF analyzer can do this application.

Oils Analysis

Sulfur, Nickel, and Vanadium in Residual Oil
These elements are monitored for either emissions or recovery purposes.

Sulfur in Coke or Carbon
There are numerous uses for Coke and Carbon, and the material becomes more valuable the lower the sulfur, with electrode grade carbon being quite valuable. This application can be done with EDXRF instruments.

Mg, P, S, Ca, Ba, Zn, Mo in Lubricating Oils
Lube oils contain a number of additives. Some additives are stabilizers, and others improve lubrication. Motor oils are the largest single class of lubricating oils in terms of volume. EDXRF has ASTM methods covering some of these additives.

S, Cl, As, Pb, Cd in Waste Oil and Waste Fuel Oil
Waste oils such as used lubrication oil are used in a number of oil fired power plants and kilns. These are monitored for toxic metals chlorine, and sulfur per environmental protection agency guidelines. EDXRF instruments can perform these measurements.

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